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Original Article
ARTICLE IN PRESS
doi:
10.25259/ANAMS_264_2024

Standard treatment workflows in orthopedics: An Indian Council of Medical Research initiative

Department of Orthopedics, All India Institute of Medical Sciences, New Delhi, India
Department of Orthopedics, Heritage Institute of Medical Sciences, Sunderpur, Nagwa, Varanasi, Uttar Pradesh, India
Department of Orthopedics, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India
Department of Orthopedics, Hamdard Institute of Medical Science and Research, New Delhi, India
Scientist C, Indian Council of Medical Research, New Delhi, India
Scientist G, Head Implementation and Delivery Research, Indian Council of Medical Research, New Delhi, India

*Corresponding author: Dr. Ashoo Grover, Scientist G and Head Implementation and Delivery Research, Indian Council of Medical Research, New Delhi, India. ashoogrover@gmail.com

Licence
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Kabra AP, Mittal S, Goel SC, Jain VK, Arya RK, Kumar S, et al. Standard treatment workflows in orthopedics: An Indian Council of Medical Research initiative. Ann Natl Acad Med Sci (India). doi: 10.25259/ANAMS_264_2024

Abstract

Objectives

In India, disparities in orthopedic care arise from variability in healthcare infrastructure, access to specialized training, and modern medical technologies. To improve uniformity and quality of treatments, the Indian Council of Medical Research (ICMR) initiated the development of standard treatment workflows (STWs) for common orthopedic conditions.

Material and Methods

A multi-disciplinary panel of national experts guided the creation of STWs. The process involved reviewing the latest literature and international guidelines, which were then adapted to local healthcare contexts. Focus was placed on prevalent conditions such as fractures, back pain, and joint diseases. External peer reviews were conducted to refine and validate the guidelines. The workflows were designed in a user-friendly, graphical format for easy implementation in various healthcare settings.

Results

The STWs provide evidence-based protocols for managing a range of orthopedic conditions. For fractures, such as ankle and distal femur fractures, the workflows guide clinicians from initial assessment to definitive surgical techniques. For degenerative conditions like knee and hip osteoarthritis, the STWs detail conservative management, surgical indications, and postoperative care. Open fractures have a dedicated workflow to stress on early interventions in post-traumatic infection prevention. The STWs are presented as concise, single-page posters to enhance accessibility and practical use in clinical settings.

Conclusion

The ICMR’s STWs represent a proactive approach to standardizing orthopedic care across India. By providing easy-to-use, evidence-based protocols, this initiative is expected to improve care quality, especially in resource-limited settings, and support ongoing training of healthcare providers.

Keywords

Guidelines
Healthcare systems
Orthopedics
Standard treatment workflows
Trauma

INTRODUCTION

India faces unique challenges in healthcare due to its vast geographical diversity, population density, and socio-economic disparities. These challenges are particularly acute in the field of orthopedic care, where the quality and availability of treatment vary significantly between urban and rural areas, and between different states.1 Such disparities are rooted in several systemic issues, including variability in healthcare infrastructure, the availability of trained healthcare professionals, and access to advanced medical technologies. The consequences are profound, affecting the outcomes of orthopedic treatments and surgeries, and thereby impacting the overall quality of the patients’ lives.2

In response to these challenges, the Indian Council of Medical Research (ICMR) has taken a significant step forward by initiating the development of standard treatment workflows (STWs) for orthopedics. The goal of these STWs is to establish a standardized protocol that can be universally applied across various healthcare settings within the country. This initiative aims not only to improve the consistency of care but also to make evidence-based treatment accessible to all segments of the population, irrespective of their geographical location or economic status.3

The need for such standardized workflows is critical in orthopedics due to the commonality and complexity of musculoskeletal conditions in India. According to previous studies, fractures and joint disorders are among the leading causes of disability in the world, and in India, the incidence of these conditions is projected to increase with the aging population.4-6 Furthermore, the burden of trauma injuries due to road traffic accidents adds to the orthopedic caseload, making effective and timely care imperative.7

The variability in orthopedic care across different regions can be attributed to several factors. Firstly, there is a significant urban-rural divide in terms of healthcare facilities. Urban centers typically have better-equipped hospitals and more skilled orthopedic surgeons compared to rural areas, where healthcare infrastructure is often lacking. This disparity results in unequal access to essential orthopedic services, including emergency care for fractures, joint replacements, and rehabilitative services.8

Secondly, the training and skills of healthcare providers vary widely. While some institutions provide advanced training in orthopedic surgery, others may not have the resources to offer such specialized training. This leads to a gap in the quality of care provided by different professionals.9 Additionally, the lack of standard treatment protocols can lead to diverse treatment approaches, which may not always be based on the best available evidence.10,11

Recognizing these issues, the ICMR’s initiative to develop STWs is a commendable effort to bridge these gaps.12 The STWs are based on a thorough review of current international guidelines, adapted to the Indian context by incorporating local clinical practices and the availability of medical resources. The process involves extensive consultations with a panel of national experts in orthopedics, who contribute diverse perspectives from across the country. This inclusive approach ensures that the workflows are comprehensive and consider the variations in medical practice settings from tertiary care centers in metropolitan cities to smaller clinics in rural areas.

MATERIAL AND METHODS

These STWs are designed to standardize care across various healthcare settings and ensure consistent, evidence-based treatment for orthopedic conditions in India. This methodology involved several key stages, incorporating input from experts in the field, peer review, and the assistance of an infographics team to create user-friendly graphical representations of the workflows. Although two STWs for orthopedics were created in the third volume of the ICMR STWs, a focused approach to include a wider range of ailments that have been commonly encountered began in 2022 [Figure 1].

Systematic flow of the process involved in creation of each STW (standard treatment workflow), ICMR: Indian Council of Medical Research.
Figure 1: Systematic flow of the process involved in creation of each STW (standard treatment workflow), ICMR: Indian Council of Medical Research.

1. Selection of expert panel

The ICMR, in partnership with the Department of Health Research (DHR), initiated the process by selecting a panel of experts. The ICMR and DHR selected the chairperson and co-chairperson for the committee. They were then tasked with the selection of specialists in the various fields of orthopedics, ranging from trauma surgeons, joint replacement specialists, spine surgeons, sports injury specialists, and pediatric orthopedicians. The panel was tasked with creating STWs that covered the most prevalent orthopedic conditions in India.

2. Assignment of topics

Once the expert panel was formed, each member was assigned a specific orthopedic condition based on their expertise. These conditions included various commonly encountered fractures (ankle, hip, distal radius fractures, and fractures around the knee), degenerative joint diseases (knee and hip osteoarthritis), back pain, neck pain, and a special focus was placed on open fractures [Table 1]. This assignment ensured that each workflow was drafted by an expert knowledgeable in the area, resulting in high-quality and clinically relevant guidelines.

Table 1: List of the 11 orthopedic ailments chosen for creating Standard treatment workflows
Orthopedic conditions chosen for the creation of standard treatment workflows

1. Ankle fractures (ICD-10: S82)

2. Distal femur fractures (ICD-10: S72.402A)

3. Fracture of distal end radius (ICD-10: S62)

4. Fracture neck of femur (ICD-10: S72.0)

5. Hip osteoarthritis (ICD-10: M16.9)

6. Intertrochanteric femoral fractures (ICD-10: S72.14)

7. Lower back pain (ICD-10: M54.2)

8. Neck pain (ICD-10: M54.2)

9. Open fractures (ICD-10: S82.891B)

10. Osteoarthritis of the knee (ICD-10: M19.9)

11. Tibial plateau fractures (ICD-10: S82.109A)

3. Drafting the initial workflow

The experts were responsible for drafting an initial version of their assigned STW. Each draft was based on a thorough review of both national and international guidelines, with adaptations made for the Indian healthcare context. The drafts were designed as concise, one-page flowcharts, making them easy to reference in clinical settings. These flowcharts covered key components such as diagnosis, treatment options, and referral pathways.

4. Internal review and discussion

The drafted STWs were reviewed in internal committee meetings, where the expert panel discussed each workflow in detail. This collaborative review ensured that each STW was comprehensive and applicable across various healthcare settings, including primary care facilities and tertiary hospitals. Feedback was incorporated, and the drafts were revised accordingly.

5. Approval by the internal committee

Following internal discussions, the revised workflows were submitted to the internal committee for approval. The committee ensured that each STW met clinical standards and that the guidelines were practical for healthcare providers in resource-limited settings.

6. Role of the infographics team

An infographics team played a crucial role in transforming the STWs into visually appealing, easy-to-follow graphical charts. This team worked closely with the expert panel to develop flowcharts that simplified the decision-making process for healthcare providers. Their efforts ensured that the workflows were not only scientifically accurate but also user-friendly. The final graphical charts were designed for both print and digital platforms, including mobile applications, making them accessible to healthcare providers across the country.

7. External peer review

Once the internal approval process was complete, an external peer review was conducted. This phase involved a broader group of professionals. The external reviewers assessed the practicality and applicability of the STWs in real-world clinical settings, identifying any areas for improvement. Feedback from this peer review was incorporated into the final drafts of the STWs.

8. Finalization and compilation in ICMR STW volume 4

After revisions from the peer review process were completed, the STWs were finalized and compiled into the 4th volume of ICMR STWs.3 The final STWs were made available in both print and digital formats. The graphical charts developed by the infographics team were integral in making the workflows accessible and understandable across a wide range of healthcare settings, from primary health centers to specialized orthopedic clinics.

RESULTS

In collaboration with the ICMR, 11 STWs were created to provide a standardized treatment protocol and optimize the management of various orthopedic conditions across India. These STWs address common fractures, degenerative joint diseases, and chronic pain syndromes prevalent in the Indian population. The primary aim was to ensure that treatment protocols are accessible, evidence-based, and applicable in different healthcare settings, from primary care centers to tertiary hospitals. The STWs were designed in a user-friendly format, allowing for easy reference by healthcare providers, and include protocols for acute trauma management, long-term care, and surgical interventions where appropriate. Below is a detailed breakdown of each STW.13

1. Ankle fractures (ICD-10: S82)

Ankle fractures, caused by both high-energy trauma and low-energy twisting injuries, are classified using the Weber and Lauge-Hansen systems. Initial management involves Advanced Trauma Life Support protocols, followed by imaging for fracture classification. Stable fractures are treated conservatively, while unstable fractures require surgical fixation, using screws, plates, or tightropes based on the specific fracture type.13

2. Distal femur fractures (ICD-10: S72.402A)

These fractures are common after high-energy trauma and fragility fractures in the elderly. The workflow emphasizes restoration of joint alignment, with surgical options such as intramedullary nailing or locking plate fixation, depending on the fracture configuration. Complex fractures might require dual plating or retrograde nailing. Early mobilization post-surgery is encouraged to prevent stiffness.14

3. Fracture of distal end radius (ICD-10: S62)

Distal radius fractures are frequently seen in elderly patients with osteoporosis. The STW recommends closed reduction and immobilization for stable fractures. For unstable fractures, volar plating or percutaneous pinning is advised. Follow-up involves regular imaging to monitor healing and alignment. Post-cast removal, physical therapy is initiated to restore wrist function.15

4. Fracture neck of femur (ICD-10: S72.0)

Timely surgical intervention is critical for femoral neck fractures, especially in the elderly, to avoid avascular necrosis. Surgery should be performed within 48 hours using internal fixation for younger patients or arthroplasty (hemi or total hip replacement) for elderly or displaced fractures. Early mobilization is stressed to enhance recovery and minimize complications.16

5. Hip osteoarthritis (ICD-10: M16.9)

The management of hip osteoarthritis involves a combination of conservative measures, such as physical therapy and non-steroidal anti-inflammatory drugs (NSAIDs), with surgical intervention (total hip arthroplasty) for patients with advanced disease. This workflow emphasizes patient education, weight loss, and strengthening exercises to maintain joint function and delay disease progression.17

6. Intertrochanteric femoral fractures (ICD-10: S72.14)

For intertrochanteric fractures, surgical treatment is recommended using either a dynamic hip screw or a proximal femoral nail, depending on the fracture stability. In severe osteoporotic cases, arthroplasty might be necessary. The STW stresses early mobilization post-surgery to prevent common complications such as deep vein thrombosis.18

7. Lower back pain (ICD-10: M54.2)

This STW emphasizes conservative management of lower back pain with physical therapy, lifestyle modification, and NSAIDs. Advanced imaging and specialist referral are advised for patients with red flag signs like neurological deficits. Surgical intervention is reserved for severe cases unresponsive to conservative management.19

8. Neck pain (ICD-10: M54.2)

The neck pain STW provides a conservative approach, highlighting physical therapy and muscle relaxants. For patients with acute pain, immobilization is recommended initially. Red flags such as radiculopathy or neurological symptoms necessitate further imaging and specialist evaluation. Surgical options are explored for cases with persistent neurological involvement.20

9. Open fractures (ICD-10: S82.891B)

The management of open fractures focuses on preventing infection by early administration of antibiotics and surgical debridement. Early stabilization, either through external fixation or internal fixation, is critical. The STW emphasizes timely soft tissue coverage, with definitive fracture fixation planned as soon as conditions permit.21

10. Osteoarthritis of the knee (ICD-10: M19.9)

The knee osteoarthritis STW stresses conservative management initially, with recommendations for weight management, exercise, and NSAIDs. For advanced cases, total knee replacement is recommended when conservative measures fail. Surgical alternatives, such as high tibial osteotomy, are considered for younger patients with varus deformities.22

11. Tibial plateau fractures (ICD-10: S82.109A)

Tibial plateau fractures require anatomical reduction to restore joint stability. Non-displaced fractures can be managed conservatively, while displaced fractures require surgical fixation with plates and screws. Early mobilization is recommended after surgery to prevent joint stiffness. The STW advises on the use of external fixators in cases of severe soft tissue compromise.23

DISCUSSION

The development and dissemination of 11 STWs for orthopedics by the ICMR is an important milestone in improving healthcare delivery across India. These workflows, designed to provide standardized, evidence-based protocols, offer significant benefits for streamlining the management of common musculoskeletal conditions. In a healthcare landscape as diverse as India’s, the need for standardized guidelines that ensure consistency in diagnosis and treatment cannot be overstated.10,11

The STWs are crucial for reducing variability in orthopedic care, especially in rural and underserved areas where access to specialized orthopedic surgeons is limited.8 The workflows focus on common conditions such as fractures, osteoarthritis, and degenerative spine conditions, conditions that account for a large proportion of orthopedic complaints in India. By providing step-by-step flowcharts and decision-making algorithms, the STWs make it easier for specialist and non-specialist healthcare providers, including general practitioners, to follow evidence-based treatment protocols.24,25 This ensures that patients receive the same quality of care, whether they are being treated in a primary healthcare center or a tertiary hospital.26

One of the most valuable aspects of the STWs is their ability to simplify complex decision-making processes, particularly for healthcare providers in rural or resource-constrained settings. This can be especially important in emergency trauma situations, where timely and appropriate interventions can prevent complications and improve recovery outcomes. The structured approach provided by the STWs helps bridge the gap between specialist and non-specialist care, ensuring that all patients, regardless of their location, receive appropriate and timely treatment.24,27

Additionally, the integration of digital tools could play a crucial role in enhancing the reach of these workflows. By making the STWs available on mobile platforms or through telemedicine, healthcare providers in remote areas could access real-time, evidence-based guidelines at the point of care. This would be particularly valuable in emergency situations, where immediate access to treatment protocols could make a significant difference in patient outcomes.28,29

While the current set of STWs is highly effective for managing common orthopedic conditions, there is potential for future expansion. More complex conditions, such as polytrauma cases, advanced reconstructive surgeries, and sports injuries, are not currently covered in the STWs. Future editions could address these gaps by including more comprehensive guidelines for handling such specialized cases. By expanding the scope of the STWs to include complex cases, the ICMR could further improve patient outcomes in specialized settings, such as tertiary hospitals and trauma centers.

Despite their strengths, the STWs have certain limitations. They primarily focus on basic orthopedic conditions, and as a result, may not provide sufficient guidance for managing complex surgical interventions or multi-disciplinary care required for advanced cases. For example, cases involving polytrauma patients or the need for specialized surgical techniques are beyond the scope of these workflows. This limits their applicability in tertiary care centers or for complex cases requiring specialized expertise.

Moreover, ensuring that the STWs are regularly updated is critical. As advancements in clinical practices and technology continue to evolve, the workflows will need to reflect these changes. The challenge lies in ensuring that updates are effectively disseminated across India’s healthcare system, especially in rural or remote areas where access to updated medical guidelines can be limited.

CONCLUSION

The introduction of the orthopedic STWs by the ICMR is a significant advancement in standardizing care for musculoskeletal conditions in India. By offering clear, evidence-based protocols, these workflows help to ensure that healthcare providers across the country can deliver consistent and high-quality care. Although there are limitations, such as the exclusion of complex cases and the need for regular updates, the STWs provide a strong foundation for improving orthopedic care in India. With further expansion and technological integration, these workflows have the potential to significantly improve patient outcomes across the country.

Acknowledgment

We would like to thank Mr Dhiraj Kumar, Mrs Sarita Kumari and Mr Mohan Kant from the Indian Council of Medical Research for their help with regards to formulating images and graphics for the standard treatment workflows.

Authors’ contributions

APK: Concepts and design, acquisition and analysis of data, manuscript preparation and editing; SM: Concepts and design, acquisition and analysis of data, manuscript editing; SCG, VKJ, RKA, SK, SS: Concepts and design; data acquisition and interpretation, manuscript revision; AG: Concepts and design; data acquisition and interpretation; Manuscript revision, Guarantor.

Ethical approval

Institutional Review Board approval is not required as no human subjects were involved in the study. The study describes the process undertaken to create standard treatment workflows.

Declaration of patient consent

Patient’s consent not required as there are no patients in this study.

Conflicts of interest

Dr. Vijay Kumar Jain is on the Editorial Board of the Journal.

Use of artificial intelligence (AI)-assisted technology for manuscript preparation

The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.

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